Aprepitant CAS NO.170729-80-3

DMSO ≥107mg/mL Water Aprepitant, with CAS 170729-80-3, is an antiemetic chemical compound that belongs to a class of drugs call…

DMSO ≥107mg/mL Water <1mg/mL Ethanol ≥7mg/mL

Aprepitant, with CAS 170729-80-3, is an antiemetic chemical compound that

belongs to a class of drugs called substance P antagonists (SPA).

Aprepitant (CAS 170729-80-3) is effective in helping to prevent CINV because

it antagonizes the NK1 receptor. This receptor is located at the brain stem nuclei of

the dorsal vagal complex and is a crucial part of the regulation of vomiting.

This is due to the receptor binding with substance P. Aprepitant (CAS 170729-80-3) can be used to treat acute and delayed chemotherapy-induced nausea and vomiting (CINV) and for prevention of postoperative nausea and vomiting.